Hello, my 5 year old female guinea pig Crunchie who is part of a herd of 7 lady pigs suddenly appeared to be heaving when breathing on Christmas Eve. We took her to the emergency vets (Battleflatts at Stamford Bridge who are very very good with guineas) and his best guess was an Uri had become a LRI and turned into pnuemonia. We treated her for 2 weeks with Septrim(?) and we were instructed to return to the vet if there was no improvement. There was improvement in that she stopped heaving when breathing but she would sneeze repeatedly and after say 3 sneezes a white snot ball would shoot out of her nose and land on the floor. We went back to the vet and he prescribed Metacam, Doxycycline and Baytril for 3 weeks. All this time she gradually lost weight going from 1000g down to 900g in the space of a month. Her appetite is the same. No more or less hungry. Not drinking any more or less either. Her poo and wee remain normal. After a week on the new medication she stopped sneezing up the white snot balls, however, she would have a wet left nostril only. The sneezing stopped. We started feeding her critical care when she dropped to 850g. She had blood taken at the vets and it showed no kidney failure or heart problem. She had x-rays which showed nothing and he checked her teeth and they are fine. The vet is baffled. Two weeks on from that and she is off all medication and no sneezing, no white snot, no clear wetness on left nostril. Her poo and wee is fine. Her appetite and drinking remain unchanged. But she keeps losing weight. She is down to 750g now despite me giving her an average of 30ml of critical care each day. She runs around with the others and doesn't look I'll except being skinny and having a puffy coat. Her eyes look fine. I am so baffled as is the vet if anyone has any idea what is wrong please post. We are back at the vets tomorrow night.