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Cisapride Tablets - Mg To Ml

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Beans&Toast

Beans&Toast

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Toast is on 0.2 mls Cisapride a day. Until now I've had it in liquid form but there's been an issue with the suppliers and can't get a hold of it for a few months so I've been given tablets instead.

I'm getting myself confused as how to change mgs into mls... my vet explained it but I'm not sure I understood him.

The tablets are 2.5mg... If I mix 1 tablet with 2mls of water and give 0.8mls does that equal 0.2mls of liquid Cisapride?


This is hurting my head :hmm::blink:
 
That's simple maths, but you would need to know what's the concentration, ie mg/ml of the liquid Cisapride? I can calculate if you give me the concentration :)
 
Powerpigs said:
That's simple maths, but you would need to know what's the concentration, ie mg/ml of the liquid Cisapride? I can calculate if you give me the concentration :)
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Not so simple for me :blink: The liquid she gets is 5mg/ml of which she gets 0.2ml twice a day. And one tablet is 2.5mg.. :hmm:
 
Okay, I'll try to explain as I go :)

She gets 0.2ml of liquid, which has 5mg/ml --> you calculate 0.2ml * 5mg/ml = 1mg. So she gets 1mg of the active ingredient, that's what her dose should include in mgs.

When you mix 1 tablet of 2.5mg with 2ml of water, you'll have 2.5mg / 2ml = 1.25mg/ml concentration for your self made liquid.

If you give 0.8 ml of this new liquid, it'll be 0.8ml * 1.25mg/ml = 1mg. So it's exactly the same dose as with the original liquid. Does this line up with what your vet said?
 
Powerpigs said:
Okay, I'll try to explain as I go :)

She gets 0.2ml of liquid, which has 5mg/ml --> you calculate 0.2ml * 5mg/ml = 1mg. So she gets 1mg of the active ingredient, that's what her dose should include in mgs.

When you mix 1 tablet of 2.5mg with 2ml of water, you'll have 2.5mg / 2ml = 1.25mg/ml concentration for your self made liquid.

If you give 0.8 ml of this new liquid, it'll be 0.8ml * 1.25mg/ml = 1mg. So it's exactly the same dose as with the original liquid. Does this line up with what your vet said?
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Thank you so much, maths is absolutely not my strong point at all...

He said to make up a couple of days worth, from what I can understand he meant mixing 1 tablet with 2mls water and giving 0.8mls twice a day and that should be the same as 0.2mls of the liquid suspension..

So that makes sense then, 0.8mls of the water solution with one 2.5mg tablet equals 0.2mls of liquid Cisapride..?
 
Beans&Toast said:
Thank you so much, maths is absolutely not my strong point at all...

He said to make up a couple of days worth, from what I can understand he meant mixing 1 tablet with 2mls water and giving 0.8mls twice a day and that should be the same as 0.2mls of the liquid suspension..

So that makes sense then, 0.8mls of the water solution with one 2.5mg tablet equals 0.2mls of liquid Cisapride..?
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Yes, 0.8ml of the water solution is the same as 0.2ml of liquid Cisapride according to my calculations, when you mix 1 tablet to 2ml of water.

I'm an engineer, so at least according to my papers I should know some maths :mal: :))
 
Tigermoth said:
I agree. In nursing we use the calculation

[you]What you want [/you] X What it's in
What you've got

Therefore
You want a 1 mg dose. You have a 2.5 mg tablet and it is in 2ml water.

[you]1[/you] X 2
2.5

Which equals 0.8ml.
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Aaah thank you. That makes sense putting it that way. Kind of :P
 
Okay so slight issue... the tablets aren't soluble in water :(

If I give it a really good mix it seems like it has desolved into the water but after a few seconds it separates... any other suggestions as to how I can give this? :hmm:
 
Hmm, have you tried warm water? At least generally everything is more soluble in warm rather than cold water. Or can you cut or grind the tablets into smaller pieces or even powder before adding the water?
 
It's a tiny little tablet, smaller than a tic tac.. Don't think cutting it would work.

I haven't tried warm water, I'll give it a go.

As soon as I took it out the bottle I didn't think it would be soluble, It's got a plastic like coating to it :hmm:
 
That's too bad :hmm: Hopefully the warm water works, I'm out of any other ideas as of now.
 
Swissgreys said:
Crush the tablet as finely as possible, and then mix it with a very small amount of fruit puree, then offer it on a teaspoon.
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The only issue with this is that she isn't getting the whole tablet. It was to be crushed and mixed with a specific amount of water to ensure she gets to correct dosage.. and it's such a tiny tablet that I can't split it :(
 
I was about to say you need to grind it down finely then mix with something that has more viscocity than water; usually they are suspended in a syrup when you get them from the vets, maybe they could let you have some x
 
Poppy'sMum said:
I was about to say you need to grind it down finely then mix with something that has more viscocity than water; usually they are suspended in a syrup when you get them from the vets, maybe they could let you have some x
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What do you mean by syrup? It was previously a liquid suspension but problems with suppliers means they can only get a hold of the tablets for now, I'm not sure what they'd be able to give me? X
 
When vets make their own meds up they crush the tablet, grind with a pestle & mortar then mix the finely ground tablet with a plain syrup suspension, so there is no splitting of the contents, the ingredient stay evenly suspended. You need to contact your vet & ask them for some tomorrow, explain it doesn't dissolve in water x
 
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