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Sterile Cystitis Questions

HollysKingdom

Junior Guinea Pig
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Good morning, this isn’t urgent, but I could do with some advice please.

Bandit has been getting treatment from our vet since the Friday after Christmas when she was doing red pees.They’ve checked a urine sample and there were no crystals or bacteria (this is a new level to me, I’d previously understood piggy bladder problems were infection or stones). She had cat metacam for a week, seemed fine, stopped for a week, more red pee. Consulted vet again, was advised to continue metacam for 10 to 14 days and get a supplement. She suggested Oxbow urinary support (except there’s supply issues) but not Cystease as it’s designed for cats, there’s no scientific research using it for guinea pigs and we don’t know the dosage (her words, not mine).

Anyway, we’re now on day 10 of 1kg cat-sized loxicom dose every 12 hours, and. day 4 of sliding from Science Selective Grain-free nuggets to Piggie Parcels joint and bladder support pellets. Bandit seemed fine again, enjoys taking metacam from a syringe and seems somehow calmer and more relaxed since eating the new pellets.

But, about 10pm yesterday she went to bed and sat there squeaking. I sat her on a white towel on my lap, and there was more red pee, her tummy was very sore, squeaking “don’t touch”.

This morning she is fine again, popcorns and zoomies to say good morning, eating, drinking, had her metacam dose, behaving normally. I’ve phoned the vet and they are giving me more metacam to use for another week before they will want to see her again.

I’m now wondering if starch/sugars in her diet are a cause. The issue started after they’d had a carrot cottage for Christmas (Minx’s carrot and nugget mine 🙄) and yesterday’s pain was after they’d had green oat readigrass in the afternoon, I don’t know if these piggies have had that before, and they don’t normally get carrots.

So, questions…

Is it likely to be diet-related? Maybe she is sensitive to something that doesn’t affect the other two.

Should I ignore the vet and try Cystease anyway?

Will cranberries help, if I can get her to eat/drink them?

Apologies for the amount of text, needed to explain xx
 
I'm sorry to hear this.

Cramberries will not help with piggies with uti and it won’t help sterile cystitis. The sugars may in fact make things worse

Yes Sterile cystitis seems to be set off by a change in the diet so if they don’t normally get carrots then yes it is possible it has caused this flare.

When a piggy has sterile cystitis, metacam is needed for life at a maintenance dose along with glucosamine. The dose can then be increased during a flare and once the flare has passed it can go back down to maintenance dose.
It will take several weeks of glucosamine for it to have an effect and help ease symptoms.
Cystease is something very commonly used amongst forum piggies with this issue.
 
I'm absolutely not the most experienced about this but the one thing I do know is that it takes a couple of weeks for the glucosamine levels to build up. This is what makes them more comfortable by soothing the bladder.
My Sir George had a squeaky wee last week (the first one I heard) so I gave him Johnson 4 joints (instead of cystease) as a booster for a few days as he has the joint support pellets too and (fingers crossed) he seems fine now. Obviously if he gets bad he will be getting seen by the vet.
This is just my experience, I hope it helps.
 
Thank you, fingers crossed the new pellets will help her. I’m gonna have to talk to the vet about metacam doses and duration, wish me luck.

Also, I will be even more scrupulous about what they eat xx
 
Hi, i’m adding to this thread cos its the same issue, just changed a bit.

Bandit and I visited the vet on Thursday taking a pee sample with us, to see how the metacam and glucosamine-containing pellets are helping her. There were still no crystals in the sample but this time the vet found bacteria. She also took a conscious (sitting wedged in a box) x-ray and found what looked like 2 stones - one very round one and another rice-grain shape potentially in her uretha.

Back we went again on Saturday morning for a sedated x-ray and ultrasound, psyching ourselves up for possible surgery next tuesday 😨. And… the stones that were there on Thursday have vanished! She seems to have peed them out and lost them.

So, we’re still giving metacam and now co-trimoxazole (sulfatrim? sticky banana stuff, I hate it - Bandit) and doing another sample in a week.

I’m confused but so glad she didn’t need surgery. And I’m still blaming the carrot cottage, flippin’ expensive Christmas present that was.
 
Hi,

My girl Peanut has just recently had a UTI and she was recommended to take cystease x1 a day, where it be syringed mixed with water or sprinkled on food. Also, I use the oxbow joint support as well as it has a higher amount of glucosamine then the bladder support and it has turmeric which is anti inflammatory (1 to 2 tablets per day). Glucosamine is just good to give everyday as it lubricates the bladder walls.

I would also change her diet to a low calcium one, which includes low calcium pellets and potentially filtering her water as it contains minerals including calcium.

I’ve finished my pigs round of co-trimaxozole and luckily there’s been no flares as of yet. Fingers crossed that it’s bacterial and not sterile 🤞🏻

Good luck
 
Hi,

My girl Peanut has just recently had a UTI and she was recommended to take cystease x1 a day, where it be syringed mixed with water or sprinkled on food. Also, I use the oxbow joint support as well as it has a higher amount of glucosamine then the bladder support and it has turmeric which is anti inflammatory (1 to 2 tablets per day). Glucosamine is just good to give everyday as it lubricates the bladder walls.

I would also change her diet to a low calcium one, which includes low calcium pellets and potentially filtering her water as it contains minerals including calcium.

I’ve finished my pigs round of co-trimaxozole and luckily there’s been no flares as of yet. Fingers crossed that it’s bacterial and not sterile 🤞🏻

Good luck

Thank you 🤗 that’s reassuring. I’m in the process of switching to the piggy parcels joint support pellets (low calcium and high glucosamine, yay!). The vet doesn’t want me to use cystease.

We’ve been feeding the low calcium diet recommended in the forum guides since Nala (then aged nearly 5) had bladder stone surgery (and almost died) in 2021. And I’ve been giving my pets Brita-filtered water since, well forever.

Which is why I’m confused about Bandit. I thought I had the diet right, and the other two are fine. I can only guess that she must have managed to eat more than her fair share of the dried carrot on the cottage roof.

Lets hope the antibiotics, metacam and new pellets sort it all out for her 🤞
 
Hiya, more to add to this, starting to feel like Bandit and I are going round in circles. So, she finished her course of co-trimoxazole, and a week later stopped taking metacam and produced a pee sample in which the vet found no bacteria or crystals. Yay! Then about a week ago she peed some blood and was in pain peeing. Back to the vet again with a sore tummy and another sample, again clear.

We’ve now just finished another 5 days of .25ml cat metacam twice daily, so today I am watching her like a hawk keeping an eye on her, so far so good 🤞 Any bets on how many days before I’m on the phone to the vets again?

Photos - marauding round demanding lunch, bowl of grass and veggies, and siesta time.
 

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This is sounding like sterile cystitis. Antibiotics and pain meds stop and a flare comes back. Antibiotics can suppress but won’t cure as there is no bacteria to kill.

Treatment is lifelong daily metacam and glucosamine (feliway cystease is recommended).
 
Thank you, its been a possibility all along 😢 And then later this afternoon I found this…

Days before phoning vet again = 0. They’ve advised another 7 days of metacam to see if that calms it down. While we’re doing that, is there any value in upping the amount of glucosamine in her diet? She’s been having 10 grams of the piggie parcels urinary support pellets for about the past month. The first vet we saw didn’t want me to use cystease (see the beginning of this thread), I’ve bought some anyway 🤫 because of the advice here. How much should she be having?
 

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It’s about finding a level of glucosamine which works as a maintenance dose in her case. It can be a capsule a day, going up to two during a flare.
It takes several weeks for glucosamine to build up.
 
Ok, thank you 🤗

I’m gonna give it a try tomorrow morning, they’ve had enough of my fussing for now (just did a big cage clean and I’m tired 🥱)
 
Hi, it’s Amanda from Piggie Parcels 👋 Just to say, not to feed cystease along side the pellets. 10g of the pellets already contain a high level of glucosamine, much more than you will find in one capsule of the cystease. So if you are feeding the pellets, don’t give another glucosamine supplement 😊 and as mentioned, it can take 6 weeks for the glucosamine to build up and start supporting the bladder wall.
I hope your piggie feels better soon. If you want to talk about levels of supplements in the pellets just send me a message x
 
Hi, it’s Amanda from Piggie Parcels 👋 Just to say, not to feed cystease along side the pellets. 10g of the pellets already contain a high level of glucosamine, much more than you will find in one capsule of the cystease. So if you are feeding the pellets, don’t give another glucosamine supplement 😊 and as mentioned, it can take 6 weeks for the glucosamine to build up and start supporting the bladder wall.
I hope your piggie feels better soon. If you want to talk about levels of supplements in the pellets just send me a message x

Ah, ok, thank you. Too much of a good thing with supplements then. I reckon we’re coming up to 6 weeks of eating the pellets anyway.

Gonna plod on with the metacam xx
 
Our girl has SC.

She’s currently also on Cerenia, to see if that makes her more comfortable as despite the twice daily dog Metacam she still seemed a bit hunchy after being handled to give her medication.

So she’s on daily Dog Metacam, Cerenia and Glucosamine (Johnson’s 4Joints Liquid).

She was getting red staining which I’ve linked to fresh forage ( rasberry leaves, nettle
Leaves, strawberry leaves) and any dried forage ( hazel leaves, birch leaves) she’s not used to having. Before SC she could have it but not anymore, tried giving her small amounts but it would trigger the red staining every time.
 
Oh, oops, I meant to keep this thread up-to-date (another of the things that don’t stay in my head lately).

Here’s where we are now…

I have a prescription for 6 months of cat Metacam to get it online. Bandit is currently having 0.16 ml twice daily, I’d been gradually reducing it, but she was squeaking yesterday and left a couple of orange/red spots on the fleece, so we’ll stick with this for a while and see.

We’ve been feeding about 10g of Piggy Parcels urinary and joint support pellets daily, which should be sufficient glucosamine.

The vet suggested looking at Bandit’s stress - ensuring she is not being bullied and is getting her share of food. Those are unlikely, she is the dominant one and bullies the others. It seems to me that she gets anxious about food not appearing when she expects it, not just wheeking but teeth chattering and agitation (maybe historically they didn’t have regular mealtimes).

I’ve bought this Pet Remedy spray, again at the vets’ recommendation, but I’m not comfortable with it - I don’t like using strong scents around them.

Bandit’s last season went on the several days, with everypig being unpleasant to one another. Since then they’ve all been much calmer. I think she’s a bit young for ovarian cysts (not 2 yet) but I wonder if a hormone imbalance would cause IC.

So basically, she is doing ok at the moment, as long as she gets regular metacam.
Our girl has SC.

She’s currently also on Cerenia, to see if that makes her more comfortable as despite the twice daily dog Metacam she still seemed a bit hunchy after being handled to give her medication.

So she’s on daily Dog Metacam, Cerenia and Glucosamine (Johnson’s 4Joints Liquid).

She was getting red staining which I’ve linked to fresh forage ( rasberry leaves, nettle
Leaves, strawberry leaves) and any dried forage ( hazel leaves, birch leaves) she’s not used to having. Before SC she could have it but not anymore, tried giving her small amounts but it would trigger the red staining every time.

I’ve not heard of Cerenia, must ask vets about it, thank you.

And I agree with you about foods being a trigger, seemed to be dried carrot for Bandit.

Whew, thats a lot of text. I hope all my loopy ideas help someone xx
 

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