Most of them don't like taking meds... Baytril smells pretty nasty, I'm sure there's a reason they don't like it! The method I usually use is to put the piggy on my lap, facing away from me. Then I stand the piggy up on her hand legs with my left hand supporting her belly and her back pressed to my stomach. Then I can reach around with the right hand and syringe the meds into the side of her mouth, in the space between the incisors and molars. After that, I will give her a treat of some kind so it ends on a positive note and takes some of the nasty taste out of her mouth. I do find that it gets easier with practice, both because you will know what you're doing and because your pig will realize that there is no escape! Make sure you also pick up the pig for lots of other reasons, like snacks and cuddles, so that he/she does not associate you only with medication. She will forgive you! One of my pigs has been on a LOT of antibiotics for bladder issues and then an abscess, plus I had to squeeze and irrigate the abscess every day for weeks on end, and she still loves me!