Back in May there was blood in my guinea pigs urine and he was crying and straining when passing stool, so I obviously took him to the vet. She took an X-ray and confirmed there was no stone and gave him Trimethoprim Sulfa .3mL twice a day for two weeks because she said it was probably a UTI. He was better for about a month, then he started crying and straining again and I saw spots of blood in his cage so I Took him back in June: she took an X-ray again confirmed there was no stone again and she gave him Meloxicam .38 mL this time once a day for 14 days because she had already given him an antibiotic and thought it might be cystitis. Meloxicam is an anti-inflammatory. He was still crying and straining every other day though and after a week I saw spots of blood in his cage for 4 days straight, so I immediately took him back (this was three weeks ago) This time she did a procedure on him in order to send his urine to a lab for testing. She told me as soon as my guinea pig was “out” because of the anesthesia he peed a little on the table before the procedure, but that she was still able to get a little urine for the test which she hoped would be enough. She sent me home with Baytril .35mL twice a day for two weeks, a stronger antibiotic then the first one. She called me after a week and said the Urine sample came back negative and that since he was responding well to Baytril (as in he stopped bleeding and crying and straining as much) to give it to him for an additional week. Well 4 days after she called he started crying and straining every other day again, although in those 3 weeks I only saw blood in his cage four days. I didn’t call her because I thought maybe I should give Baytril till the end of the three weeks to work. He finished the antibiotic treatment yesterday though and today I heard him straining when he passes stool. It’s weird, he doesn’t do it every time, but I wished I didn’t hear it at all. It Breaks my heart and I don’t know what else to do. I feel like I’ve done everything I can. I don’t know if it’s worth mentioning but he had surgery back in February for a bladder stone. Have you ever had this happen with any guinea pig? Should I change vets? I feel bad for the little guy. Thanks and sorry this message is so long.