• Discussions taking place within this forum are intended for the purpose of assisting you in discussing options with your vet. Any other use of advice given here is done so at your risk, is solely your responsibility and not that of this forum or its owner. Before posting it is your responsibility you abide by this Statement

Guinea pig still unwell after a treated ear infection

julieandruth

Junior Guinea Pig
Joined
Oct 11, 2025
Messages
11
Reaction score
26
Points
145
Location
Southampton
Hi! Ruth is my 2-3 year old rescue pig I got last summer, on the 21st of jan, in the evening I noticed she had a very slight head tilt but it was barely noticeable, by the next morning she was completely unwell, the head tilt got 10x worse, she was constantly falling over to the side, couldn't eat, walk, or do anything, she was just sat in the middle of the cage completely out of it, and clearly very dizzy, so of course I quickly crushed up some pellets and made some diy "critical care" as I had none at the time, and syringe fed her while waiting until 9 am for the vets to open so I could call them. They ended up squeezing me in for a 4pm appointment, and she did in fact end up having an ear infection (the vet also said she most likely has vestibular disease as well due to her funky eye movement). She was prescribed 0.55ml of enrofloxacin/baytril, and 0.14ml of meloxicam, both to be given twice a day for a week straight, as well as critical care which the vet managed to give me but told me to order more. I also gave her 1ml x3 daily of fibreplex after 2 days as her appetite wasn't getting any better, but her ear infection did end up clearing up after 4-5 days. Unfortunately I did end up running out of fibreplex right before the last day which might've upset her gut again, but she seemed to be coping and she was eating and drinking, though still felt a bit less energetic than before. I did notice one day that she was puffed up and not eating, and she also had not pooped in a full day. I got recommended to give her a warm bath and a belly massage as it could've potentially been bloat, which would make sense as they had pak choi the day before (which they've always had 2x per week with no problems), lo and behold she got better after that, was releasing a bit of gas and finally pooping, and we were back to the point after antibiotics, where she was eating and drinking fine, but something still didn't 100% feel right and she just didn't have the same energy or excitement as before, especially with veggies. I went to pets at home to get her probiotics as fibreplex would've taken a while to come again and I also just wanted a cheaper option, so I ended up buying vetark pro c probiotics for her, and I was giving her 1 scoop mixed with a bit of water by syringe everyday, though that didn't seem to work very well. She's currently functioning like a normal pig, eating, etc but she definitely does not have the appetite or energy like she always does. I've been weighing her throughout all of this, during the antibiotics her weight seemed to be fluctuating pretty normally, after her bloat she lost 44g in one day, and ever since that happened her weight has been slowly going down every single day, not by a huge amount, but it's been a little while now and she's currently at the lowest weight she has every been, 1057g, when she's usually around 1200-1250g, and I can definitely feel her spine and bones a lot more. I've also noticed she's been drinking way more, which makes me pretty worried that it's something to do with her kidneys, or she has diabetes, especially as she is still eating veggies, hay, etc, while continuously losing weight. Her butt is also quite soiled and I think she has a bit of irritation on her feet from the urine, though I can't tell if that's from her sitting in one place not doing a lot, or if she is actually peeing more. I'm currently giving her critical care and fibreplex which doesn't seem to be doing a whole lot, so I will get a vet appointment for her tomorrow most likely. The only thing I'm just extremely confused about is if all of this is connected to the ear infection and antibiotics, or if this is just a coincidence and she's just having a whole lot of problems in one short timespan, but I'm really hoping she doesn't have something worse going on now like kidney disease/failure.
 
Hi

Please step in with feeding support asap. Antibiotics can be appetite killers; especially baytril/enrofloxacin.
- Weight and Weight Loss Explained: BMI, Weighing, Poos and Feeding Support Levels
- How to Improvise Feeding Support in an Emergency
- All About Syringe Feeding and Medicating Guinea Pigs with Videos and Pictures

A permanent head tilt can be the result of an ear infection if it has done some permanent damage to ear structure.

A sudden rise but persistent rise in water intake that is not due to a change of conditions (sudden cold or hot spells; increased indoors heating) or medication should be investigated.
Kidney function or less commonly, diabetes may be things your vet will consider, depending on their findings on the examination table.
All About Drinking, Bottles and Dehydration (has a chapter on drinking changes and related illnesses)

Our care tips for guinea pigs with mobility issues also apply to piggies with excessive urination, including regular 1-2 times daily change of bedding in the denning areas, urine scald care, foot and genitalia/belly monitoring etc.
Here are the practical how-to details in full: Looking After Guinea Pigs With Limited or No Mobility

Wishing you all the best. Please take the time to read the links, as they contain all the practical how-to care tips at home that I cannot type out in full. I hope that our care information can help you in addition to the necessary vet trip.
 
Hi

Please step in with feeding support asap. Antibiotics can be appetite killers; especially baytril/enrofloxacin.
- Weight and Weight Loss Explained: BMI, Weighing, Poos and Feeding Support Levels
- How to Improvise Feeding Support in an Emergency
- All About Syringe Feeding and Medicating Guinea Pigs with Videos and Pictures

A permanent head tilt can be the result of an ear infection if it has done some permanent damage to ear structure.

A sudden rise but persistent rise in water intake that is not due to a change of conditions (sudden cold or hot spells; increased indoors heating) or medication should be investigated.
Kidney function or less commonly, diabetes may be things your vet will consider, depending on their findings on the examination table.
All About Drinking, Bottles and Dehydration (has a chapter on drinking changes and related illnesses)

Our care tips for guinea pigs with mobility issues also apply to piggies with excessive urination, including regular 1-2 times daily change of bedding in the denning areas, urine scald care, foot and genitalia/belly monitoring etc.
Here are the practical how-to details in full: Looking After Guinea Pigs With Limited or No Mobility

Wishing you all the best. Please take the time to read the links, as they contain all the practical how-to care tips at home that I cannot type out in full. I hope that our care information can help you in addition to the necessary vet trip.
Unfortunately, it's worse news than I expected 😞 She's seen the vet today and the vet felt a bunch of lumps on all of her lymph nodes, meaning she very very likely had lymphoma. She took a fluid sample from the lymph nodes and they should be back by the end of this week to confirm if it's definitely cancer, but it most likely is. I got given the options of doing chemotherapy, steroids, or just leaving it. I'm currently leaning more towards leaving it but I'd love some thoughts about chemo/steroids
 
I’m sorry you’ve had this possible diagnosis. Sending healing vibes to your piggy and hugs to you.

What a long and happy life she has had with you. ❤️
 
You need to control her weight loss before considering chemo or steroids. I am sorry to hear that your piggy is unwell, sending wishes for strength 🙏❤️
 
Unfortunately, it's worse news than I expected 😞 She's seen the vet today and the vet felt a bunch of lumps on all of her lymph nodes, meaning she very very likely had lymphoma. She took a fluid sample from the lymph nodes and they should be back by the end of this week to confirm if it's definitely cancer, but it most likely is. I got given the options of doing chemotherapy, steroids, or just leaving it. I'm currently leaning more towards leaving it but I'd love some thoughts about chemo/steroids

BIG HUGS

I am so very sorry. What a total blind-siding shock from such an unexpected direction. :yikes:

Treatment decisions depend very much how aggressive and how wide spread the lymphoma is. There is a whole spectrum.

The most aggressive form can spread very quickly and kill within days of coming up but we have had also piggies on here with a milder form, which had not spread much, that lived for months on steroids, which seems to be at the moment the most successful way of treating mild to medium forms of lymphoma.
So far, traditional cancer treatments have been rarely undertaken and have generally not worked well on guinea pigs.

I guess your vet has excluded cervical lymphadenitis because lumps are not just in the neck but all over the body where lymph nodes should be?


If you are considering any end of life decisions, then you may find this link below helpful. There is no right or wrong in this area; especially when you are dealing with a very painful, incurable illness. It is more of a matter of which factors weigh greater with you than others but they all have their rightful place.
The questions are just there to help you to make any decisions feeling less overwhelmed and emotionally conflicted and to ease the big guilt/second-guessing mind loop at the onset of the grieving process which you are currently experiencing. If the lumps have come up so quickly in a number of lymph nodes, then you are more likely dealing with a more aggressive form of whatever it is. :(
Operation, Terminal Care or Euthanasia? - Helpful Questions to Ask Ahead or in Hindsight

My thoughts are with you but of one thing I am sure: Ruth was lucky to find you and your love, even if she hasn't got much time with you.

Please step in with feeding support. Has your vet given you any painkillers?
Weight and Weight Loss Explained: BMI, Weighing, Poos and Feeding Support Levels
All About Syringe Feeding and Medicating Guinea Pigs with Videos and Pictures
 
BIG HUGS

I am so very sorry. What a total blind-siding shock from such an unexpected direction. :yikes:

Treatment decisions depend very much how aggressive and how wide spread the lymphoma is. There is a whole spectrum.

The most aggressive form can spread very quickly and kill within days of coming up but we have had also piggies on here with a milder form, which had not spread much, that lived for months on steroids, which seems to be at the moment the most successful way of treating mild to medium forms of lymphoma.
So far, traditional cancer treatments have been rarely undertaken and have generally not worked well on guinea pigs.

I guess your vet has excluded cervical lymphadenitis because lumps are not just in the neck but all over the body where lymph nodes should be?


If you are considering any end of life decisions, then you may find this link below helpful. There is no right or wrong in this area; especially when you are dealing with a very painful, incurable illness. It is more of a matter of which factors weigh greater with you than others but they all have their rightful place.
The questions are just there to help you to make any decisions feeling less overwhelmed and emotionally conflicted and to ease the big guilt/second-guessing mind loop at the onset of the grieving process which you are currently experiencing. If the lumps have come up so quickly in a number of lymph nodes, then you are more likely dealing with a more aggressive form of whatever it is. :(
Operation, Terminal Care or Euthanasia? - Helpful Questions to Ask Ahead or in Hindsight

My thoughts are with you but of one thing I am sure: Ruth was lucky to find you and your love, even if she hasn't got much time with you.

Please step in with feeding support. Has your vet given you any painkillers?
Weight and Weight Loss Explained: BMI, Weighing, Poos and Feeding Support Levels
All About Syringe Feeding and Medicating Guinea Pigs with Videos and Pictures
I'll wait until I get the results to choose her treatment options, but I think I'm leaning more towards just leaving it and doing palliative care for her. I'm really scared of chemo or steroids messing up her little body and causing her more suffering but then again, I don't know much about either of those and would love opinions/useful info. I really want her to have a good quality of life instead of quantity, but I will consider steroids or chemo depending on how progressed the cancer is and if we can somehow do it in a way that gives her the least suffering, even if it requires her to have a bunch of other meds. I don't want to prolong her life by a couple of weeks/months just so she could be miserable and be unable to live like a normal guinea pig in that time, it would most likely affect julie (her friend) too. Right now she seems to be coping and eating hay and some forage, I think last night she's taken a liking to me hand feeding her veggies while holding her so I'll be doing that, probably prevents julie from stealing her food too LOL Also, yes the vet ruled out cervical lymphadenitis I think, I also doubt it would be something caused by a bacterial infection as my other pig would have it by now too. I'm going to need to buy more syringes for feeding today as the old ones broke but no she doesn't have any painkillers currently, I have some from her ear infection but I won't be giving it to her without the vet confirming. If she does end up passing naturally in her home or with me then that's okay, but if the cancer does get bad to the point it stops her from eating, moving, etc completely, then I will consider euthanasia for her own sake, so she doesn't have to slowly suffer until death. I just hope she's had a good life in the 8 short months she's been with me.

Ruth today, eating her hay :nod:
IMG_0375.webpIMG_0379.webp
 
Ruth is gorgeous. I love my ginger cresteds and have had a string of them over the years - and I do miss them as I have been winding down my numbers gradually over the past few years.

I do agree with you; that is my general attitude as well with my own piggies but it is usually something that you rather grow into over the years.

If several lymph nodes are already affected in such a short time, it is generally not good news. I am so sorry. Lymphoma is not a nice thing and I don't wish it on any piggy or their owners! :(
 
Ruth is gorgeous. I love my ginger cresteds and have had a string of them over the years - and I do miss them as I have been winding down my numbers gradually over the past few years.

I do agree with you; that is my general attitude as well with my own piggies but it is usually something that you rather grow into over the years.

If several lymph nodes are already affected in such a short time, it is generally not good news. I am so sorry. Lymphoma is not a nice thing and I don't wish it on any piggy or their owners! :(
Thank you x I'll update when the lab results come back to me, but I know she doesn't have long left. I checked her lumps in the middle of the night and also today afternoon, she seems to have one big lump under her chin accompanied by multiple small ones, last time it felt like 2 lumps fused together, but now it seems to have fused with a smaller one overnight, or maybe it just grew, but I'm not 100% sure. She has a medium-ish lump under her left armpit and left hip/hindleg, also with a bunch of smaller ones, her right side seems to just have clusters of little tiny ones but no bigger lumps :( To be honest as I'm writing this I've felt the lump in her hind and it seems to have grown aswell, it's quite big actually. I hope it doesn't cause her too much discomfort, I know that if the one under her chin grows and prevents her from swallowing then I'll definitely have her euthanised, as she probably won't even be able to eat from a syringe anymore. I would definitely prefer for her to pass in the comfort of her own home though and not the vets.
 
Thank you x I'll update when the lab results come back to me, but I know she doesn't have long left. I checked her lumps in the middle of the night and also today afternoon, she seems to have one big lump under her chin accompanied by multiple small ones, last time it felt like 2 lumps fused together, but now it seems to have fused with a smaller one overnight, or maybe it just grew, but I'm not 100% sure. She has a medium-ish lump under her left armpit and left hip/hindleg, also with a bunch of smaller ones, her right side seems to just have clusters of little tiny ones but no bigger lumps :( To be honest as I'm writing this I've felt the lump in her hind and it seems to have grown aswell, it's quite big actually. I hope it doesn't cause her too much discomfort, I know that if the one under her chin grows and prevents her from swallowing then I'll definitely have her euthanised, as she probably won't even be able to eat from a syringe anymore. I would definitely prefer for her to pass in the comfort of her own home though and not the vets.

HUGE HUGS

Whatever it is, it is very aggressive and you may not have time to wait for the lab results. I cannot tell you just how sorry I am and how deeply I feel for Ruth, Julie and you, knowing how devastating this is.
 
I am so sorry for the probable diagnosis 😞

I’ve had two piggies with lymphoma and I chose palliative care for both.

In Ena’s case, we lost her on the day of diagnosis as we didn’t realise that’s what she had when we had a lump removed and she chewed out her stitches. We took her to the emergency vet who explained that she chewed the stitches as the wound wasn’t healing due to the cancer so we had to help her cross the rainbow bridge. Erika lived for 3 weeks post diagnosis. Like with Ruth, all her lymph nodes became inflamed and we had a fine needle biopsy of one of the lumps which confirmed our worst fears.

We spoiled her rotten, took lots of photos and made lots of memories. We had to help her cross the rainbow bridge when the lymph nodes in her neck became so swollen that they were pressing on her windpipe making it difficult for her to breathe.

I’m so sorry I do not have better news 😞 x
 
I am so sorry for the probable diagnosis 😞

I’ve had two piggies with lymphoma and I chose palliative care for both.

In Ena’s case, we lost her on the day of diagnosis as we didn’t realise that’s what she had when we had a lump removed and she chewed out her stitches. We took her to the emergency vet who explained that she chewed the stitches as the wound wasn’t healing due to the cancer so we had to help her cross the rainbow bridge. Erika lived for 3 weeks post diagnosis. Like with Ruth, all her lymph nodes became inflamed and we had a fine needle biopsy of one of the lumps which confirmed our worst fears.

We spoiled her rotten, took lots of photos and made lots of memories. We had to help her cross the rainbow bridge when the lymph nodes in her neck became so swollen that they were pressing on her windpipe making it difficult for her to breathe.

I’m so sorry I do not have better news 😞 x
Thank you, I've accepted that her time will be soon, was expecting her to live for only 2-3 weeks as well, so I'm just trying to make a list of things to do with her before the time comes 😞 Going to make some clay paw prints with her soon x
 
Thank you, I've accepted that her time will be soon, was expecting her to live for only 2-3 weeks as well, so I'm just trying to make a list of things to do with her before the time comes 😞 Going to make some clay paw prints with her soon x
Making clay paw prints with her is a lovely idea. I am thinking of you both x
 
Sorry, quite a late update but i could only today call the vets back for the results, it is indeed lymphoma and her estimated time left is about 2 weeks to 5 weeks at the very most 😞 I can do chemo or steroids but the vet said they most likely won't do much for her anyway and she's not too keen to do it for ruth either, treatments would just cause her more suffering. So far she hasn't gotten any worse and she is still eating though x
 
Sorry, quite a late update but i could only today call the vets back for the results, it is indeed lymphoma and her estimated time left is about 2 weeks to 5 weeks at the very most 😞 I can do chemo or steroids but the vet said they most likely won't do much for her anyway and she's not too keen to do it for ruth either, treatments would just cause her more suffering. So far she hasn't gotten any worse and she is still eating though x

BIG HUGS

I am so very sorry. Try to make every remaining day special for Ruth. Love transcends time and so do precious shared memories from moments you can still both savour and enjoy.

A Practical and Sensitive Guide to Dying, Terminal Illness and Euthanasia in Guinea Pigs
Enrichment comes in so many different forms: Enrichment Ideas for Guinea Pigs

My piggies have just for instance had their first little fresh grass taster of the year from our lawn - only a little in order to not upset the gut and to allow the grass processing microbiome to wake up and to multiply as the portions are slowly getting bigger. Treats don't have to be big; all they have to do is bring a little joy. :)

There is no right or wrong whether you want to treat with what is clearly an aggressive form of cancer or whether you prefer to concentrate on maximum quality of life/minimum suffering. It has to feel right for you and Ruth. But if it helps you, I would have made the same decision as the lymphoma has come up and spread so quickly. It is one of these things you do not wish on anybody and it is very hard when your piggy draws a very short straw.

My heart goes out to you.
 
I am very sorry that your worst fears have been confirmed 😞 Make memories with her every day and cherish whatever time you and Ruth have left together. I know how heartbreaking it is but I think you’ve made the right decision x
 
Very sorry to hear such sad news. I hope you get some good snuggle times in the time left. She is a beautiful piggy ❤🙏
 
I’m so sorry you have gotten this diagnosis. I hope she has some more happy days with you. Spoil her rotten. ❤️
 
Back
Top