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Help needed pls 3.5 year old female guinea pig with recurring urinary issues and smell

Dash_and_Ozzie_the_floofs

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Hi,

One of our guinea pigs, Ozzie (3.5 y.o longhaired sow) has been having urinary issues since like November. She also smells bad quite a lot of the time (since last week she's had 2 baths I think, We know she shouldn't be bathed that often but the smell is terrible). Her pee is thick and white. She is now the lowest weight she has been since she was less than a year old in 2023. She is now 988g, before any of this happened she was around 1100g+ I will put a timeline of events below:

November 2025: Our other guinea pig, Dash, got gut stasis/a blockage and would not eat. She kept trying to eat the wood shavings though, so we got some fleece mats (they weren't the proper ones though). With this came the start of Ozzie's problems. She smelled a lot, but we put this down to the pee soaking through the pee pad things.

Somewhere around December 2025: Dash had recovered (and stopped eating woodshavings) so we could put the woodshavings back. We thought that this would get rid of the smell, but Ozzie still smelled.

February 2026: Ozzie started squeaking when she peed, as well as the smell. We got her to the vet and she was diagnosed with a UTI. She had antibiotics and rheumocam. This stopped the smell and squeaking for a while but the smell came back quite quickly.

March: She went to the vet again, she got the same things again. At this appointment she peed and it was apparently like yogurt and smelled terrible. We booked her an ultrasound.

Later in March: She had her ultrasound. This revealed bladder sludge. She was given rheumocam and potassium citrate to try and get rid of the sludge. She is still on these.

She has been on and off smelling since then.

A few days ago: we picked her up and she peed, but it was only like a dribble/droplets and really thick and white. She also seems to be holding her pee, as every time we've picked her up she has either had a full bladder or peed on my husband.

We went to the vet and she got a stronger rheumocam prescription. This is now the strongest she can have. The vet said that if it doesn't clear up within two weeks, she will need an x-ray, and if it shows anything she might need surgery. (I'm not sure whether that is what the vet said or what my husband thinks will happen though).

So far not much has changed, she is still extremely smelly. I am very concerned as I have heard the outcomes for guinea pig surgery is not great. Is this true?

We've heard surgery is very expensive, and we've been quoted a lot of money for an x-ray (over £400 possibly) we are not sure if we have enough money for this.

My 15 year old daughter is autistic and has sensory issues. Her smell is causing worsening of them. This is stopping her interact with them as much at the moment (we are instead), which is sad because guinea pigs are her special interest.

She is on rheumocam, potassium citrate, and oxbow urinary support tablets. She has filtered water. She also has oxbow vitamin c tablets.

We are worried that she is in pain and we don't know. We don't want anything bad to happen to her. Is there anything we can do to help her (other than bathe her a lot)? Also, has anyone had any similar issues?
I was going to add photos for the guinea pig tax but I can't seem to see how to do it
 
I'm sorry about all the problems Ozzie is having. Guinea pigs hide pain very well so I'm sorry to say it is likely she is in pain too, unless any of the meds she is on are painkillers.

Guinea pig vet costs are high in the UK, compared to some other countries, but it is what it is.

I hope that one of the forum people who keep an eye on the health threads will get back to you soon since they will have much more idea than I do of what could be going on.

The only thing I could suggest is getting a second opinion from another vet and making sure it is a vet for Exotics.
 
Thank you. She has rheumocam which is an anti inflammatory, which is a pain killer like neurofen for people. The vet has upped her dose. We only go to an exotics vet, so travel 45 mins each way, rather than go to any of the vets in our town. She has been seen by two different exotics vets. Hopefully the increase in anti inflammatories will help. The vet said take her back in a couple of weeks if she is no better
 
I’m sorry to hear this

I’m wondering if the sludge is quite tightly packed and not able to flush out properly. Lots of watery veg can help encourage bigger pees but tightly packed sludge usually needs surgical removal unfortunately.
Potassium citrate is more of a support med rather than a cure. It can help to prevent more sludge (and stones) forming in some cases but it doesn’t help for anything already in existence.

Surgeries, and particularly bladder surgeries, do require an experienced vet and of course outcomes also depend on the general health of the piggy going into surgery but generally are good.

In the meantime, ensure you weigh her daily so you can monitor hay intake closely, and support feed if needed. Glucosamine can also help support the bladder

I have added a guide below which will provide further information

I hope she is ok

Wiebke's Guide to Pees and Stones
 
I'm sorry I tend not to remember the name of painkillers, so if Ozzie is on them as you say, then let's hope she isn't in pain.

If Ozzie has to go into surgery in a couple of weeks, there is a lot of info on that here on the forum which I'm sure somebody will link for you.
 
I’m sorry to hear this

I’m wondering if the sludge is quite tightly packed and not able to flush out properly. Lots of watery veg can help encourage bigger pees but tightly packed sludge usually needs surgical removal unfortunately.
Potassium citrate is more of a support med rather than a cure. It can help to prevent more sludge (and stones) forming in some cases but it doesn’t help for anything already in existence.

Surgeries, and particularly bladder surgeries, do require an experienced vet and of course outcomes also depend on the general health of the piggy going into surgery but generally are good.

In the meantime, ensure you weigh her daily so you can monitor hay intake closely, and support feed if needed. Glucosamine can also help support the bladder

I have added a guide below which will provide further information

I hope she is ok

Wiebke's Guide to Pees and Stones
Thank you that's very helpful
 
Hi

I am very sorry about your ongoing issues.

The strong smell could be a sign of a bacterial bladder infection, either urine or bladder walls.

Otherwise, I agree with what @Piggies&buns has said.

PS: I have had several bladder stones removed from piggies of mine; in one case twice - and that was 20 years ago - and in another with a rabbit sized enormous 11 mm round stone. All piggies have survived the op.
 
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