Where did the recommendation for glucosamine come from? I see a lot online, but very little scientific study. The only data I can find is a single retrospective study that states "There are some
preventive treatments described in the literature, although, in our study we only investigated the use of potassium citrate and, for the first time, the influence of glucosamine. According to our results, animals treated with a conventional treatment plus potassium citrate presented a significantly better response to the treatment. This information is interesting and relevant, as it supports the idea that is frequently suggested in the literature regarding the potential effect of this supplementation to bind calcium and decrease its activity [
5,
8,
25]. Therefore, the oral administration of potassium citrate at a dose of 20 mg/kg twice daily has been recommended [
8]. On the contrary,
the use of glucosamine had no significant influence on the response to treatment. Further studies, particularly of a prospective nature, will be necessary to determine this potential therapeutic impact more accurately, which has not been verified in our population."
Lower Urinary Tract Diseases in Guinea Pigs: A 14-Year Retrospective Study (2004–2018) - PMC
Good luck, and puttng Pebble on the prayer list