Hi
Pee oxidises after it leaves the body, so it usually goes an orange and then increasingly rusty colour as it dries and ages. That is nothing to worry about, as long as any drying urine patches don't have small reddish dots in the patch or - if there is a fair amount of it in the uringe - a reddish ring in a different shade on the outside. A darker pee rim in the same hue as the inside is normal as the patch dries. Blood doesn't mix evenly with blood. Please see a vet if you notice the presence of blood in urine.
The odd milky calcium pee that dries to a whiteish powdery deposit is also nothing to worry about. However, if you see them regularly on a daily or near daily basis, you are feeding a diet that is too high in calcium and that can in the longer term contribute to the build up of bladder stones and sludge since guinea pigs have naturally very alkaline urine, which makes them very prone to problems with the urinary tract. It is unfortunately not quite as straight forward as cutting any calcium out of the diet, but you may find our sample diet picture in the diet guide good starting point. Please also keep in mind that hard water can be the biggest contributor to calcium and that some pellet brands also contain a higher content of calcium than other; you really need to look at the whole food range. Follow the tips in our guide. I have made it as clear and as detailed as possible. The recommendations are based on long term experienciences.
Recommendations For A Balanced General Guinea Pig Diet