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Jack - Gradual Weight Loss - Liver Problem & Now Possible Uri?

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Pig Daddy

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Hi everyone. I have a 4-year-old boar called Jack, who lives with a pair of sows (he's neutered). Everything's been fine with them until around mid March, when we noticed that the weekly weighings were showing Jack's weight falling a bit. We took him to the vet once the net loss from stable peak weight (~1175g) reached about 50g. This vet seemed fairly unconcerned at that, checked his teeth, breathing etc. and said he couldn't see anything wrong. He suggested trying different nuggets, hay brands etc which we did, and gave the number of a more specialist vets a little further out from where we live, to call if we still had concerns.

So a few weeks pass by, with the hay & nugget variety tried (they now have 4 nugget types to chose from), and Jack was still gradually losing weight. We contacted the specialist vet as suggested, who took a blood sample to send away, plus did an X-ray because they'd thought they felt something a little out of the ordinary when they palpitated his abdomen. Ultimately the X-ray revealed nothing, but the blood tests revealed somewhat depressed protein levels, plus something (exactly what I can't recall) that indicated inflammation was present somewhere in his body. These vets certainly seemed equipped & experienced to diagnose by my inexpert estimation.

After the vet had spoken to a colleague, we had Jack back there for a scan, which revealed that the walls of the blood vessels in his liver were thickened, but with cause unknown. She prescribed Milkthistle as (I gather) a protective rather than curative treatment, with a promise she'd investigate the condition and get back to us. This was about 2 weeks ago, at which point Jack was down to 1030g.

During that time the Milkthistle & special attention with a wide variety of different food seemed to be working; the weight loss was definitely halted and he'd even put a modest amount back on to 1060g. However last night we took him out for Milkthistle & a weigh, and he'd lost 30g in the 24h since last weigh. We also noticed that one of his nostrils had a light-yellow discharge with snuffling noise. Whisked him off to the emergency vet and ended up with a (£125) shot of Baytril, and to attend our normal vet in the morning. No suggestion of difficulty breathing or congestion in lungs. We were also advised to separate Jack from the girls for a week, which we have.

This morning we noticed that he was sneezing and some fairly opaque 'snot' was being discharged - and from right nostril only again. We took him to the local vet straight away, and he's now on 0.8ml Baytril 2.5% 1/day for 10 days + 0.13ml Metacam 1/day for 10 days. This vet seemed surprised that it was just in the one nostril and suggested that it could be something he'd sniffed up that was irritating him, rather than a URI, but prescribed the aforementioned anyway. Again, No suggestion of difficulty breathing or congestion in lungs. Mentioned possibility of flushing nose if ABs didn't do anything.

As of this evening Jack is at just over 1000g. But I've only heard him sneeze once since the vets, and there's only a very slight dampness of the nostril rather than a definite discharge as there was before. We're attempting hand feeding seriously now (had not done it aggressively to now as he seemed to be slowly gaining again) but I'm now getting very worried. He will take so much Critical Care fairly willingly, but then really kick up a fuss once he's had his fill, which is hard given our inexperience with hand feeding (I've watched the vid linked from this site, but still a bit clumsy). Will try little & often.

It's worth noting that at no point throughout had Jack shown any signs of illness obviously associated with the weight loss - he was outwardly normal or perhaps a little subdued at times, but not markedly so. However he has periodically displayed the following over the last year or so, but beginning a long time before any signs of weight loss began so I'm hesitant to definitively link any of it, and had until now pretty much dismissed them.
  • Pronounced mastication, as though something is stuck in his mouth - I've even seen fine bits of hay protruding which were definitely the culprits on those occasions. He clears it in the end but he has periods where he'll do it fairly often, and then it stops for a month or two and then he'll do it again for a period. Within the last year he's had his teeth checked three times by three vets and ruled out as a problem each time. One of the vets even remarked that his teeth were in very good condition for his age.
  • Occasional snuffling like a blocked nostril - same sound as when he was snotty yesterday. First time this happened (almost a year ago) we whisked him off to the vets and by the time he was examined it had stopped completely. I looked around a few posts in search results here and other places, and concluded it was likely something snuffled up while he's rummaging in hay. However the girls don't seem ever to make this noise.
I intend to chivvy along the specialist vet about his liver issue on Monday (5 days left of the Milkthistle) but if anyone has any similar experiences in this area then can they please offer any advice?

I believe the 'URI' treatment to be all in hand given the signs he is presenting & what's been prescribed, but again any advice about this aspect is very welcome.

DSC_0059.webp
From left: Jack, Sophie, Jess

Many thanks
Ed
 
Hi there- what gorgeous piggies!

It may well be that the URI is the cause of his current demise, and sounds like the treatment for that is under control. The only thing i could add is to give a probiotic 1-2 hours after each antibiotic dose, as baytril can be hard on the guts good bacteria.

Continue weighing him daily and syringe feeding if he isnt eating properly. Go little and often if he has a URI, and the less he takes before kicking off, the more often you will need to feed.

Complete Syringe Feeding Guide

If he deteriorates or doesnt improve within the expected time frame, it would be best to have him see the specialist vet again. If the URI symptoms clear but he still isnt right, then looking back into his liver issues would make sense.

Someone else may be along to advise you in more detail with regards to his liver problems.

Sending Jack healing vibes x
 
Hi! It sounds like it could have been something stuck in nostril rather than a URI. But with your boy having a underlying issue, it is the right decision to treat for a URI in any case.

I have lost two guinea pigs with suspected liver failure some years ago at a time when there was nothing a vet could do about it, not even reliably diagnose it. I haven't been dealing with it more recently, so I can't say whether there is now a possible treatment or not. It may well be that like with acute kidney failure, what a vet can do is still very limited. :(

Both my piggies also suffered from a slow gradual, but steady weight loss. Please start offering him additional syringe feed to slow down the weight loss. Keep in mind that baytril is an appetite dampener/killer. Give 1 pinch of probiotic 1-2 hours after the antibiotic to help prop up the guts.

Ask your vet for milkthistle if that is helping to slow down things and to buy your piggy more quality time.
 
Thanks all for the replies. Jack seems to have rebounded from the 'URI' (or whatever it was) quite quickly. The discharge only lasted a couple of days and he's put back on the weight he lost over the weekend. We're continuing with the Baytril though, to complete the course. Jack is his usual cheeky self and doesn't appear to be suffering in any way; except perhaps missing his girls, but that won't be for much longer and they can still see each other in their cages.

The specialist vets still don't have anything conclusive, but the guy who I spoke to (lead vet, small-animal specialist, sounded very knowledgeable) said he appeared to have some unknown fluid buildup in his gall bladder too. Without a biopsy they couldn't be sure what. He said that he'd not want to do a biopsy without a good chance it would diagnose something they could treat, which sounds perfectly sensible to me, but that he'd investigate further with some pathologist or other and get back to me.

In the meantime, the milk thistle appears to be of benefit and (discounting the transient ~60g loss due to the URI thing) he hasn't lost weight since starting it. So I remain hopeful that Jack can carry on with good quality of life a while yet and we'll just have to manage it as best we can going forward. I bought some milk thistle tablets and we're just going to keep giving him that.
 
Unfortunately we had to let Jack go yesterday. He seemed to be doing quite well on the Baytril, plus some Metronidazole that was subsequently supplied, and was pretty happy until Friday. However on Friday we noticed the 2 girls sitting next to him a lot and him being unusually lazy, looking a bit puffy and not much interested in food. This quite rapidly deteriorated to be anorexic with no pooping evident, and he was looking uncomfortable so we whisked him off to the vet who'd been treating this condition. They gave him pain meds and suspected bloat.

They treated for this and he eventually started passing stools though not much interested in food, but quite comfortable with the pain meds. They did a scan next day and it revealed some causes for concern, particularly a mass that had appeared. The diagnosis they had from the pathologist was either something treatable with the ABs or it was lymphoma, so this latter started to be strongly suspected. They proposed opening him up to investigate and potentially remove the mass that was present, or to put him to sleep. After a discussion around this we decided to proceed with the operation, as it wouldn't add too much to his distress, and perhaps this mass could be removed to make him comfortable and address the immediate problem to give him some more time. Unfortunately when they operated they found indications that some of his organs were diseased / inflamed and this confirmed to them, short of a biopsy, that it was indeed lymphoma that had spread quite a bit. We therefore made the call to let him go under anesthetic.

Really sad to see the little guy go. I'll put something in the Rainbow Bridge section when I have had a couple of days more to get used to it.
 
I'm so sorry for your loss. It certainly sounds as if you exhausted every avenue of hope and it was jack's time to pass over the bridge. Take care x
 
I'm so sorry! Jack was lucky to have such a dedicated owner trying anything to help him, and allowing him to pass pain free when you knew you could no longer do anything.

Sleep tight Jack x
 
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