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Uncertain about course of action with chronically ill pig

patnporridge

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Here's a tightened version:


Hi! This is a long one, so I'll try to keep it organised. I had to ask Claude AI to make it more concise as I was all over the place!

Our guinea pig Plum is around 5 years old (rescue, so we're not certain) and has become quite the medical case. A year and a half ago she had a front tooth removed after it snapped, which left her with chronic sneezing, wheezing, and a weepy eye on that side. Our exotics vet monitors her every 3–4 months and always gives her the all-clear, explaining it's just the lasting effect of the surgery. We nebulise her with F10 and saline, and she gets meloxicam when symptoms flare. Despite all this, she's a happy little pig — food-obsessed, active, full of personality.

In February she started pooping blood. She was acting completely normally, but we took her straight in. An ultrasound and X-ray didn't show anything alarming, and the vet suggested a spay as a potential solution — though without a clear diagnosis. The X-ray was touch and go as her breathing caused complications under anaesthetic, so the vet said they wouldn't operate until her breathing improved first.

She was put on Co-trimoxazole, then switched to Baytril. She stopped eating, went into gut stasis, and lost 100g in a few days. It was the worst week of my life nursing her through it, but she pulled through, and the bleeding stopped. We decided to let her rest and hope she was on the mend.

A month later, the blood is back — though again, she seems completely unbothered. The vet now wants to try Karidox before booking surgery. She's only been on it two days, but she's already going off her food and we're scared of gut stasis again. I've emailed the vet with our concerns and have held off on tonight's and tomorrow morning's dose — the gut stasis felt closer to losing her than anything else she's been through.

We're stuck in a difficult loop: she can't have surgery until her breathing improves, her breathing won't improve without antibiotics, but the antibiotics keep sending her into gut stasis.

We love her enormously, and we're realistic that 2026 might be the year we lose her. Honestly, I'd rather she go peacefully from an internal complication while still happy and eating than suffer through another bout of gut stasis or not wake up from anaesthetic. When I tentatively raised the idea of quality of life — and whether treatment was still worth pursuing — the vet seemed taken aback, so I'm not sure where we stand on that front.

Has anyone been in a similar situation? Any advice would be gratefully received.
 
So sorry that you are in such a difficult situation
It’s clear that Plum is loved very much.

I have had piggies who were terminally ill and my response is usually to treat if it will help, otherwise to ensure they have comfortable happy days for whatever time is left.
I have taken lots of photos and tried to make every day happy.

Go with your heart in any decision you make.

Hugs 🤗
 
Sorry to hear that things are so difficult for you and your lovely piggy. I find probiotics such as Pro C and Biolapis Fibreplex have been helpful for my piggy Polo who is on Baytril. Also poop soup from his healthy companion. You may have tried these already of course. I hope your piggy gets stronger and gets better soon 🙏❤️
 
So sorry to hear, and I agree that quality of life matters and, in the end, when to let go is a heart-based decision. I wonder about the after-effects of the surgery though and whether or not there is a chronic persistent infection in the dental/sinus area contributing to the breathing problems. I agree that probiotics may offer some relief and might consider a vitamin/mineral supplement if digestion is compromised, perhaps even Vitamin C supplementation to support small vessel stability and prevent GI bleeding to due capillary fragility. Good luck and piggy is in my prayers ;)
 
Perhaps I should’ve mentioned - she already takes a vitamin c tablet most days anyway, and our pigs have a bottle with vitamin water in in their cage too. Both times on the antibiotics when she’s stopped eating as much she’s been on fibreplex, as well as a gut stimulant to keep things moving, as well as critical care to supplement the small amount of food she is eating.
 
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