Hadley was on a course of sulfatrim for 10 days- her main symptoms were just noisy breathing. She got better on the meds, but had it recur after three or so days with no meds. The vet then put her on 20 days of sulfatrim.... again, she did well on, then had symptoms recur about a week after stopping. She is just now finishing up a course of Baytril for 10 days, as they decided to change the antibiotics. I am hoping the change did the trick for her, as I really do not want to prolong her Baytril, as it bugs her stomach a bit. Maybe if the original antibiotic is not clearing things, the vet would consider changing to another one because not all bacteria are susceptible to all antibiotics. Was the vet able to do a culture to see what organism is causing the problem? We weren't able to do that with Hadley, as she really didn't have any nasal discharge to culture, but it would have simplified things if we could have!